Drug Therapy Guidelines

• Abbreviated Criteria Abbreviated Criteria: Carbaglu, Dificid, Gralise, Hetlioz, Jetrea, Kanuma, Keveyis, Mulpleta, Nuedexta, Nuplazid, Panretin, Strensiq, Sylvant, Syprine, Xatmep, Xuriden
• Abiraterone Abiraterone acetate (abiraterone acetate, Zytiga™, Yonsa®)
• Abraxane Abraxane® (paclitaxel protein-bound particles)
• Actemra Actemra® (tocilizumab)
• Actimmune Actimmune® (interferon gamma 1b)
• Adakveo Adakveo® (crizanlizumab-tmca)
• Adalimumab Adalimumab (Hadlima™ [adalimumab-bwwd], Hulio® [adalimumab-fkjp], Humira® [adalimumab], Hyrimoz™ [adalimumab-adaz])
• Adcetris Adcetris™ (brentuximab vedotin)
• Addyi Addyi™ (flibanserin)
• Aduhelm Aduhelm™ (aducanumab-avwa)
• Afrezza Afrezza® (insulin human)
• Alecensa Alecensa® (alectinib)
• Aliqopa Aliqopa™ (copanlisib)
• Alpha-1 Proteinase Inhibitors (Human) Alpha-1 Proteinase Inhibitors (Human): Aralast NP, Glassia, Prolastin-C®, Zemaira®
• Alunbrig Alunbrig™ (brigatinib)
• Amantadine ER Amantadine ER (Gocovri®, Osmolex ER™)
• Amifampridine Amifampridine (Firdapse®, Ruzurgi)
• Ampyra Ampyra® (dalfampridine)
• Antiemetic Agents Antiemetic Agents: Zofran®/ODT® (ondansetron/ondansetron ODT/ondansetron oral solution), Zuplenz® (ondansetron oral film), granisetron, Sancuso® (granisetron topical), Anzemet® (dolasetron), Emend® (aprepitant), aprepitant, Akynzeo® (netupitant/palonosetron), Varubi® (rolapitant)
• Apokyn Apokyn® (Apomorphine)
• Appetite Suppressants Appetite Suppressants (Anorexiants) & Weight Loss Agents: Adipex-P®, phentermine, phendimetrazine, Didrex®, benzphetamine, Suprenza®, diethylpropion, Xenical®, Qsymia®, Contrave®, Lomaira™, Saxenda®
• Arcalyst Arcalyst® (rilonacept)
• Arzerra Arzerra® (ofatumumab)
• Asparagine Specific Enzymes Asparagine Specific Enzymes: Asparlas™ (calaspargase pegol-mknl), Oncaspar® (pegaspargase)
• Aubagio Aubagio® (teriflunomide)
• Austedo Austedo® (deutetrabenazine)
• Ayvakit Ayvakit (avapritinib)
• Azacitidine Azacitidine Intravenous: Vidaza® (azacitidine), azacitidine Oral: Onureg® (azacitidine)
• Azedra Azedra® (iobenguane I 131)

• Bafiertam Bafiertam™ (monomethyl fumarate)
• Balversa Balversa™ (erdafitinib)
• Bavencio Bavencio® (avelumab)
• Beleodaq Beleodaq® (belinostat)
• Bempedoic Acid Bempedoic Acid (Nexletol [bempedoic acid], Nexlizet [bempedoic acid, ezetimibe])
• Benlysta Benlysta® (belimumab)
• Beovu Beovu® (brolucizumab-dbll)
• Besponsa Besponsa™ (inotuzumab ozogamicin)
• Bevacizumab Bevacizumab (Avastin® [bevacizumab], Mvasi® [bevacizumab-awwb], Zirabev™ [bevacizumab-bvzr])
• Blenrep Blenrep™ (belantamab mafodotin-blmf)
• Blincyto Blincyto® (blinatumomab)
• Bonsity Bonsity (teriparatide)
• Bortezumib Bortezomib (bortezomib, Velcade® [bortezomib])
• Bosulif Bosulif® (bosutinib)
• Botulinum Toxins Botulinum Toxins: Botox® (onabotulinumtoxinA), Dysport™ (abobotulinumtoxinA), Myobloc® (rimabotulinumtoxinB), Xeomin® (incobotulinumtoxinA)
• Braftovi Braftovi™ (encorafenib)
• Breyanzi Breyanzi® (lisocabtagene)
• Brineura Brineura™ (cerliponase alfa)
• Brukinsa Brukinsa™ (zanubrutinib)
• Cablivi Cablivi® (caplacizumab-yhdp)
• Cabometyx Cabometyx® (cabozantinib)
• Calcitonin Gene Related Peptide (CGRP) Antagonists - Acute Treatment Nurtec ODT (rimegepant), Ubrelvy (ubrogepant)
• Calcitonin Gene Related Peptide (CGRP) Antagonists - Preventive Treatment Aimovig™ (erenumab-aooe), Ajovy™ (fremanezumab-vfrm) , Emgality™ (galcanezumab-gnlm), Vyepti ™ (eptinezumab-jjmr)
• Calquence Calquence ® (acalabrutinib)
• Cambia Cambia™ (diclofenac potassium for oral solution)
• Caprelsa Caprelsa® (vandetanib)
• Chenodal Chenodal™ (chenodiol)
• Cholbam Cholbam® (cholic acid)
• Cimzia Cimzia® (certolizumab pegol)
• Cinqair Cinqair® (reslizumab)
• Colony Stimulating Factors - Filgrastim Agents Colony Stimulating Factors (CSFs): Filgrastim Agents Granix® (Tbo-filgrastim), Neupogen® (filgrastim), Nivestym™ (filgrastim-aafi)
• Colony Stimulating Factors - Pegfilgrastim Agents Colony Stimulating Factors (CSFs): Pegfilgrastim Agents Udenyca™ (pegfilgrastim-cbqv), Nyvepria™ (pegfilgrastim-apgf), Ziextenzo™ (pegfilgrastim-bmez)
• Cometriq Cometriq® (cabozantinib)
• Compounded Medications Compounded Medications
• Copiktra Copiktra™ (duvelisib)
• Corlanor Corlanor® (ivabradine)
• Cosentyx Cosentyx® (secukinumab)
• Cotellic Cotellic™ (cobimetinib)
• Crysvita Crysvita® (burosumab-twza)
• Cyramza Cyramza® (ramucirumab)
• Dacogen Dacogen® (decitabine), decitabine
• Daklinza Daklinza™ (daclatasvir)
• Darzalex Darzalex™ (daratumumab), Darzalex Faspro™ (daratumumab and hyaluronidase-fihj)
• Daurismo Daurismo™ (glasdegib)
• Desmopressin acetate Desmopressin acetate (Nocdurna®, Noctiva™)
• Diacomit Diacomit® (stiripentol)
• Dojolvi Dojolvi™ (triheptanoin)
• Doptelet Doptelet® (avatrombopag)
• Doxepin cream Doxepin cream: doxepin 5% cream, Prudoxin™, Zonalon®
• Duopa Duopa™ (carbidopa/levodopa enteral suspension)
• Dupixent Dupixent® (dupilumab)
• Durysta Durysta™ (bimatoprost) intracameral implant

• Egrifta Egrifta®, Egrifta SV™ (tesamorelin)
• Elaprase Elaprase® (idursulfase)
• Elzonris Elzonris™ (tagraxofusp-erzs)
• Emflaza Emflaza™ (deflazacort)
• Empliciti Empliciti™ (elotuzumab)
• Endari Endari™ (L-glutamine)
• Enhertu Enhertu® (fam-trastuzumab deruxtecan-nxki)
• Enspryng Enspryng™ (satralizumab-mwge)
• Entyvio Entyvio® (vedolizumab)
• Epaned Epaned® (enalapril powder for oral solution)
• Epclusa Epclusa™ (sofosbuvir and velpatasvir); Sofosbuvir/Velpatasvir (authorized generic)
• Epidiolex Epidiolex® (cannabidiol)
• Erbitux Erbitux® (cetuximab)
• Erectile Dysfunction (ED) Agents Erectile Dysfunction (ED) Agents: Cialis® (tadalafil), tadalafil, Levitra® (vardenafil), vardenafil, Viagra® (sildenafil), sildenafil, Caverject® (alprostadil), Edex® (alprostadil), Muse® (alprostadil), Staxyn® (vardenafil), Stendra™ (avanafil)
• Ergot Alkaloids Ergot Alkaloids: dihydroergotamine mesylate, Migranal (dihydroergotamine mesylate)
• Erivedge Erivedge® (vismodegib)
• Erleada Erleada™ (apalutamide)
• Erythropoetin Stimulating Agents Erythropoiesis-Stimulating Agents (ESAs): Epogen® (epoetin alfa), Procrit® (epoetin alfa)
• Esbriet Esbriet® (pirfenidone)
• Etanercept Etanercept (Enbrel® [etanercept], Eticovo [etanercept-ykro])
• Evenity Evenity™ (romosozumab-aqqg)
• Everolimus Everolimus (Afinitor® [everolimus], Afinitor DISPERZ® [everolimus], everolimus)
• Evrysdi Evrysdi™ (risdiplam)
• Exon Skipping Therapies for Duchenne Muscular Dystrophy Exon Skipping Therapies for Duchenne Muscular Dystrophy - Exondys 51™ (eteplirsen), Vyondys 53™ (golodirsen), Viltepso® (viltolarsen), Amondys 45™ (casimersen)
• Fabrazyme Fabrazyme® (agalsidase beta)
• Farydak Farydak® (panobinostat)
• Fasenra Fasenra™ (benralizumab)
• Ferriprox Ferriprox® (deferiprone)
• Fertility Medications Bravelle®, Cetrotide®, Clomid**, clomiphene**, Follistim AQ®, Ganirelix®, Gonal-F®, human chorionic gonadotropin, leuprolide, Menopur®, Novarel®, Ovidrel®, Pregnyl®, progesterone in oil
• Fintepla Fintepla® (fenfluramine)
• Firdapse Firdapse® (amifampridine)
• Forteo Forteo® (teriparatide)
• Galafold Galafold™(migalastat)
• Gamifant Gamifant™ (emapalumab-lzsg)
• Gattex Gattex® (teduglutide [rDNA origin])
• Gaucher’s Disease Agents Gaucher’s Disease Agents: Cerdelga® (eliglustat), Cerezyme® (imiglucerase), Elelyso® (taliglucerase alfa), Vpriv (velaglucerase alfa), Zavesca® (miglustat), miglustat
• Gavreto Gavreto™ (pralsetinib)
• Gazyva Gazyva® (obinutuzumab)
• Gilenya Gilenya™ (fingolimod)
• Gilotrif Gilotrif® (afatinib)
• Givlaari Givlaari™ (givosiran)
• Glassia Glassia [Alpha-1 Proteinase Inhibitor (Human), Intravenous]
• Gleevec Gleevec® imatinib
• Global Authorization Policy
• Gonadotropin-Releasing Hormone Agonists Gonadotropin-Releasing Hormone Agonists- Eligard®, Fensolvi® (leuprolide acetate), Lupron®, Lupron-Depot®, Lupron Depot-Ped®, Lupaneta® (leuprolide, norethindrone pack), Lutrate® Depot, Triptodur™ (triptorelin), Trelstar® (triptorelin, including Depot and LA), Synarel ®(nafarelin acetate)
• Grastek Grastek® (Timothy Grass Pollen Allergen Extract)
• Growth Stimulating Drugs Growth Stimulating Drugs: Norditropin®, Genotropin®, Humatrope®, Omnitrope®, Nutropin®, Saizen®, Serostim®, Zomacton™, Zorbtive® (somatropin, recombinant growth hormone)

• H.P. Acthar Gel H.P. Acthar® Gel (repository corticotropin)
• Halaven Halaven™ (eribulin mesylate)
• Harvoni Harvoni® (ledipasvir and sofosbuvir); Ledipasvir and Sofosbuvir (authorized generic)
• Hemlibra Hemlibra® (emicizumab-kxwh)
• Hepatitis C Antivirals Pegasys®,Peg-Intron®, ribavirin, Ribasphere®, Ribasphere Ribapak®, Rebetol®, Intron-A®
• Hereditary Angioedema (HAE) Agents Hereditary Angioedema (HAE) Agents: Berinert® (C1 esterase inhibitor [human]), Cinryze® (C1 esterase inhibitor [human]), Haegarda® (C1 esterase inhibitor [human]), icatibant Kalbitor® (ecallantide), Firazyr® (icatibant), Ruconest® (C1 esterase inhibitor [recombinant]), TakhzyroTM (lanadelumab-flyo)
• Horizant Horizant® (gabapentin enacarbil ER)

• Ibrance Ibrance® (palbociclib)
• Iclusig Iclusig® (ponatinib)
• Idhifa Idhifa® (enasidenib)
• Ilaris Ilaris® (canakinumab)
• Ilumya Ilumya™ (tildrakizumab-asmn)
• Imbruvica Imbruvica® (ibrutinib)
• Imcivree Imcivree™ (setmelanotide)
• Imfinzi Imfinzi (durvalumab)
• Imlygic Imlygic™ (talimogene laherparepvec)
• Immune Globulin Intravenous: Asceniv, BIVIGam®, Carimune® NF, Flebogamma® DIF, Gammagard®, Gammagard® S/D, Gammaked®, Gammaplex®, Gamunex-C®, Octagam®, Panzyga, Privigen® Subcutaneous: Cutaquig®, Cuvitru™, Gammagard®, Gammaked®, Gamunex-C®, Hizentra®, HyQvia®, Xembify
• Impoyz Impoyz™ (clobetasol propionate)
• Inbrija Inbrija™ (levodopa) oral inhalation powder
• Increlex Increlex® (mecasermin)
• Infliximab Infliximab (Remicade®, Avsola(infliximab-axxq), Inflectra®/infliximab-dyyb, Renflexis™/infliximab-abda)
• Ingrezza Ingrezza™ (valbenazine)
• Inlyta Inlyta® (axitinib)
• Inqovi Inqovi® (decitabine and cedazuridine)
• Inrebic Inrebic® (fedratinib)
• Intravitreal Corticosteroid Implants Intravitreal Corticosteroid Implants: Iluvien® (fluocinolone acetonide), Ozurdex® (dexamethasone), Retisert® (fluocinolone acetonide)
• Iressa Iressa® (gefitinib)
• Istodax Istodax® (romidepsin), romidepsin
• Isturisa Isturisa® (osilodrostat)
• Jakafi Jakafi® (ruxolitinib)
• Jelmyto Jelmyto™ (mitomycin)
• Jevtana Jevtana® (cabazitaxel)
• Juxtapid Juxtapid™ (lomitapide)
• Jynarque Jynarque™ (tolvaptan)

• Kadcyla Kadcyla® (ado-trastuzumab emtansine)
• Kalydeco Kalydeco® (ivacaftor)
• Kerydin Kerydin® (tavaborole), tavaborole
• Kesimpta Kesimpta® (ofatumumab)
• Kevzara Kevzara® (sarilumab)
• Keytruda Keytruda® (pembrolizumab)
• Kineret Kineret® (anakinra)
• Kisqali Kisqali ® (ribociclib), Kisqali® Femara® Co-Pack (ribociclib; letrozole)
• Klisyri Klisyri™ (tirbanibulin)
• Korlym Korlym™ (mifepristone)
• Koselugo Koselugo™ (selumetinib)
• Krystexxa Krystexxa™ (pegloticase)
• Kuvan Kuvan® (sapropterin dihydrochloride)
• Kymriah Kymriah® (tisagenlecleucel)
• Kynmobi Kynmobi™ (apomorphine hydrochloride)
• Kyprolis Kyprolis™ (carfilzomib injection)
• Lartruvo Lartruvo™ (olaratumab)
• Lemtrada Lemtrada® (alemtuzumab)
• Lenvima Lenvima® (lenvatinib)
• Libtayo Libtayo® (cemiplimab-rwlc)
• Lidoderm Lidoderm® patch, lidocaine patch
• Lonsurf Lonsurf® (trifluridine and tipiracil)
• Lorbrena Lorbrena® (lorlatinib)
• Lumizyme Lumizyme® (alglucosidase alfa)
• Lumoxiti Lumoxiti™ (moxetumomab pasudotox-tdfk)
• Lupkynis Lupkynis™ (voclosporin)
• Lutathera Lutathera ® (lutetium Lu 177 dotatate)
• Luxturna Luxturna® (voretigene neparvovec-rzyl)
• Lynparza Lynparza® (olaparib)
• Lyrica CR Lyrica CR® (pregabalin ER)

• Macugen Macugen® (pegaptanib)
• Margenza Margenza™ (margetuximab)
• Marqibo Marqibo™ (vincristine liposomal)
• Mavenclad Mavenclad® (cladribine)
• Mavyret Mavyret® (glecaprevir and pibrentasvir)
• Mayzent Mayzent® (siponimod)
• Medical Benefit Reference Guide
• Medicare Part B Step Therapy Management Abraxane, Avastin, Beovu, Epogen, Eylea, Fulphila, Granix, Herceptin, Herceptin Hylecta, HP Acthar, Lucentis, Macugen, Neupogen, Nivestym, Procrit, Remicade, Rituxan, Rituxan Hycela, Soliris, Treanda, Ziextenzo
• Mekinist Mekinist™ (trametinib)
• Mektovi Mektovi®(binimetinib)
• Mepsevii Mepsevii™ (vestronidase alfa-vjbk)
• Monjuvi Monjuvi® (tafasitamab-cxix)
• Movantik Movantik® (naloxegol oxalate)
• Mozobil Mozobil™ (plerixafor)
• MS Agents Multiple Sclerosis (MS) Self-Injectable Agents: Avonex®, Betaseron®, Copaxone®, Extavia®, glatopa™, Plegridy™, Rebif®
• Myalept Myalept™ (metreleptin)
• Mycapssa Mycapssa® (ocreotide)
• Mylotarg Mylotarg™ (gemtuzumab ozogamicin)
• Natpara Natpara® (parathyroid hormone)
• Nerlynx Nerlynx™ (neratinib)
• Neumega Neumega® (oprelvekin)
• Nexavar Nexavar® (sorafenib)
• Ninlaro Ninlaro® (ixazomib)
• Northera Northera® (droxidopa)
• Nourianz Nourianz™ (istradefylline)
• Nplate Nplate® (romiplostim)
• Nubeqa Nubeqa® (darolutamide)
• Nucala Nucala® (mepolizumab)
• Nutritional Supplements Nutritional Supplements, Enteral Formulas
• Ocaliva Ocaliva® (obeticholic acid)
• Ocrevus Ocrevus™ (ocrelizumab)
• Odactra Odactra™ (House Dust Mite [Dermatophagoides farinae and Dermatophagoides pteronyssinus]Allergen Extract)
• Odomzo Odomzo® (sonidegib)
• Ofev Ofev® (nintedanib)
• Off-Label Drug Use Policy
• Olumiant Olumiant®(baricitinib)
• Olysio Olysio™ (simeprevir)
• Ongentys Ongentys® (opicapone)
• Onpattro Onpattro™ (patisiran)
• Opdivo Opdivo® (nivolumab)
• Opioid Management Opioid Management
• Oralair Oralair® (Sweet Vernal, Orchard, Perennial Rye, Timothy, and Kentucky Blue Grass Mixed Pollens Allergen Extract)
• Orencia Orencia® (abatacept)
• Orgovyx Orgovyx™ (relugolix)
• Oriahnn Oriahnn™ (elagolix, estradiol, and norethindrone acetate; elagolix)
• Orilissa Orilissa™ (elagolix)
• Orkambi Orkambi® (lumacaftor/ivacaftor)
• Otezla Otezla® (apremilast)
• Oxbryta Oxbryta™ (voxelotor)
• Oxervate Oxervate™ (cenegermin-bkbj)
• Oxlumo Oxlumo™ (lumasiran)

• Padcev Padcev™ (enfortumab vedotin-ejfv)
• Palforzia Palforzia (Peanut [Arachis hypogaea] Allergen Powder-dnfp)
• Palynziq Palynziq® (pegvaliase-pqpz)
• PCSK9 Inhibitors PCSK9 Inhibitors: Praluent™, Repatha™
• Pemazyre Pemazyre™ (pemigatinib)
• Pemetrexed Pemetrexed (Alimta®, Pemfexy™)
• Penicillamine Therapy Penicillamine Therapy – Cuprimine®, Depen®, penicillamine
• Perjeta Perjeta™ (pertuzumab)
• Phesgo Phesgo™ (pertuzumab, trastuzumab, and hyaluronidase-zzxf)
• Piqray Piqray® (alepelisib)
• Polivy Polivy™ (polatuzumab vedotin-piiq)
• Pomalyst Pomalyst® (pomalidomide)
• Portrazza Portrazza® (necitumumab)
• Poteligeo Poteligeo® (mogamulizumab-kpkc)
• Preferred Drug Step Therapy Angiotensin Receptor Blockers (ARBs); Antipsychotics, 2nd generation; BPH (alpha-antagonists); Beta Agonist Inhalers; Calcipotriene Agents; Carbinoxamine, ; CNS Stimulants; Conjupri; Consensi; Constipation Agents; Desvenlafaxine; DPP-4 Inhibitors; Drizalma Sprinkle; Duexis; Duobrii; Elyxyb; Epaned; Epinephrine Products; Fenofibrates; Hemady; Impeklo, Incretin Mimetics; Inhaled Combinations; Inhaled Corticosteroids; Insulin; Insulin, Basal; Intranasal Steroids; Katerzia; Metformin ER Products; Muscle Relaxants, Select Non-Steroidal Anti-Inflammatory Drugs (NSAIDs); Niacin IR; Niacin ER; Osteoporosis Agents; Ozobax; Pancreatic Enzymes; Pizensy; Prexxartan, Prostaglandin Analogs; Proton Pump Inhibitors (PPIs); Qbrelis; Rayos (prednisone delayed-release); Renin Inhibitors; Rho Kinase Inhibitors; Riluzole; Selective Serotonin Reuptake Inhibitors (SSRIs); Sympazan; Test Strips for Blood Glucose; Testosterone Replacements; Select Tetracyclines; Topical Antifungals; Topical Dermatologics; Urinary Agents; Verzacloz; Vimovo; Yupelri
• Prevymis Prevymis™ (letermovir)
• Procysbi Procysbi® (cysteamine bitartrate delayed release capsules)
• Promacta Promacta® (eltrombopag)
• Provenge Provenge® (sipuleucel-T)
• Pulmonary Arterial Hypertension (PAH) Agents Pulmonary Arterial Hypertension (PAH) Agents: Revatio™ (sildenafil), Ventavis® (iloprost), Tracleer®(bosentan), Letairis™ (ambrisentan), Adcirca®(tadalafil), Tyvaso® (treprostinil), Remodulin®(treprostinil), Flolan®/Veletri® (epoprostenol),Adempas® (riociguat), Opsumit® (macitentan),Orenitram® (treprostinil), Uptravi® (selexipag), Alyq (tadalafil)
• Qbrelis Qbrelis™ (lisinopril oral solution)
• Qbrexza Qbrexza™ (glycopyrronium 2.4% cloth)
• Qinlock Qinlock™ (ripretinib)
• Qutenza Qutenza® (8% capsaicin patch)

• Radicava Radicava® (edaravone)
• Ragwitek Ragwitek® (Short Ragweed Pollen Allergen Extract)
• Ravicti Ravicti™ (glycerol phenylbutyrate)
• Reblozyl Reblozyl® (luspatercept-aamt)
• Relistor Relistor® (methylnaltrexone bromide)
• Retevmo Retevmo™ (selpercatinib)
• Remicade Remicade® (infliximab)
• Revcovi Revcovi™ (elapegademase-lvlr)
• Revlimid Revlimid® (lenalidomide)
• Reyvow Reyvow™ (lasmiditan)
• Rinvoq Rinvoq™ (upadacitinib)
• Rituximab Rituximab (Rituxan® [rituximab], Rituxan Hycela® [rituximab/hyaluronidase human, recombinant], Ruxience™ [rituximab-pvvr], Truxima® [rituximab-abbs])
• Rozlytrek Rozlytrek™ (entrectinib)
• Rubraca Rubraca® (rucaparib)
• Rydapt Rydapt® (midostaurin)
• Samsca Samsca® (tolvaptan)
• Sarclisa Sarclisa® (isatuximab-irfc)
• Scenesse Scenesse® (afamelanotide)
• Sedative Hypnotics Sedative Hypnotics: zolpidem, Ambien®, zolpidem CR, Ambien CR®, zaleplon, Sonata®, DayvigoTM, Lunesta®, Rozerem®, ramelteon, EdluarTM, ZolpimistTM, doxepin (generic Silenor®), Silenor®, Intermezzo®/zolpidem SL, Belsomra®
• Signifor Signifor®, Signifor® LAR (pasireotide)
• Siliq Siliq™ (brodalumab)
• Simponi Simponi®, Simponi Aria® (golimumab)
• Sitavig Sitavig® (acyclovir)
• Skyrizi Skyrizi™ (risankizumab-rzaa)
• Sodium oxybate Sodium oxybate (Xyrem® [sodium oxybate], Xywav™ [calcium, magnesium, potassium, and sodium oxybates])
• Solaraze Solaraze®, diclofenac 3% gel
• Soliris Soliris™ (eculizumab)
• Somavert Somavert® (pegvisomant)
• Sovaldi Sovaldi™ (sofosbuvir)
• Spinraza Spinraza™ (nusinersen)
• Spravato Spravato™ (esketamine) nasal spray
• Sprycel Sprycel® (dasatinib)
• Stelara Stelara® (ustekinumab)
• Stivarga Stivarga® (regorafenib)
• Sucraid Sucraid® (sacrosidase)
• Sunosi Sunosi™ (solriamfetol)
• Sutent Sutent® (sunitinib)
• Sylatron Sylatron™ (peginterferon alfa-2b)
• Symdeko Symdeko™ (tezacaftor/ivacaftor)
• Symlin Symlin® (pramlintide acetate)
• Symproic Symproic® (naldemedine)
• Synagis Synagis® (palivizumab injection)
• Synribo Synribo® (omacetaxine mepesuccinate)

• Tabrecta Tabrecta™ (capmatinib)
• Tafinlar Tafinlar® (dabrafenib)
• Tagrisso Tagrisso™ (osimertinib)
• Taltz Taltz® (ixekizumab)
• Talzenna Talzenna™ (talazoparib)
• Tarceva Tarceva® (erlotinib), erlotinib
• Targretin Targretin®/bexarotene capsules, Targretin® gel
• Tasigna Tasigna® (nilotinib)
• Tavalisse Tavalisse™ (fostamatinib)
• Tazverik Tazverik™ (tazemetostat)
• Tecartus Tecartus™ (brexucabtagene autoleucel)
• Tecentriq Tecentriq® (atezolizumab)
• Tecfidera Tecfidera® (dimethyl fumarate)
• Technivie Technivie™ (ombitasvir, paritaprevir, ritonavir)
• Tegsedi Tegsedi™ (inotersen)
• Temodar Temodar®, temozolomide
• Tepezza Tepezza (teprotumumab-trbw)
• Tepmetko Tepmetko™ (tepotinib)
• Tetrabenazine Tetrabenazine (Xenazine® [tetrabenazine], tetrabenazine)
• Tibsovo Tibsovo® (ivosidenib)
• Tolsura Tolsura™ (itraconazole)
• Topical Immunomodulators Topical Immunomodulators- Elidel® (pimecrolimus cream), Eucrisa® (crisaborole ointment), pimecrolimus cream
• Torisel Torisel® (temsirolimus), temsirolimus
• Transmucosal Immediate Release Fentanyl Abstral® (sublingual tablet), Actiq® (oral transmucosal lozenge), fentanyl powder, Fentora® (buccal tablet), Lazanda® (nasal spray), Onsolis® (buccal soluble film), Subsys® (sublingual spray)
• Trastuzumab Trastuzumab (Herceptin® [trastuzumab], Herceptin Hylecta™ [trastuzumab and hyaluronidase-oysk], Kanjinti™ [trastuzumab-anns], Ogivri[trastuzumab-dkst], Ontruzant (trastuzumab-dttb), Trazimera™ [trastuzumab-qyyp])
• Tremfya Tremfya™(guselkumab)
• Trikafta Trikafta™ (elexacaftor, tezacaftor, ivacaftor; ivacaftor)
• Triptans Triptans: almotriptan, Amerge®, Axert®, Frova®, Imitrex® and sumatriptan tablets/nasal spray/injection, Maxalt/MLT®, naratriptan, Onzetra™ Xsail™, Relpax® and eletriptan tablets, rizatriptan/ODT, Sumavel®, Tosymra™, Treximet®, Zembrace™ SymTouch™, zolmitriptan/ODT tablets, Zomig/ZMT® tablets/nasal spray
• Trodelvy Trodelvy™ (sacituzumab govitecan-hziy)
• Trogarzo Trogarzo™ (ibalizumab-uiyk)
• Tukysa Tukysa™ (tucatinib)
• Turalio Turalio™ (pexidartinib)
• Tykerb Tykerb® (lapatinib)
• Tymlos Tymlos® (abaloparatide)
• Tysabri Tysabri® (natalizumab)
• Uloric Uloric® (febuxostat)
• Ultomiris Ultomiris™ (ravulizumab-cwvz)
• Unituxin Unituxin™ (dinutuximab)
• Uplizna Uplizna™ (inebilizumab-cdon)
• Valchlor Valchlor® (mechlorethamine gel)
• Vectibix Vectibix® (panitumumab)
• Venclexta Venclexta® (venetoclax)
• Verquvo Verquvo™ (verciguat)
• Verzenio Verzenio™ (abemaciclib)
• Viekira Viekira Pak™ (ombitasvir, paritaprevir, and ritonavir tablets; dasabuvir tablets), Viekira XR™ (dasabuvir, ombitasvir, paritaprevir, and ritonavir) extended-release tablets
• Vimizim Vimizim® (elosulfase alfa)
• Vitrakvi Vitrakvi® (larotrectinib)
• Vizimpro Vizimpro® (dacomitinib)
• Vosevi Vosevi™ (sofosbuvir, velpatasvir, and voxilaprevir)
• Votrient Votrient® (pazopanib)
• Vumerity Vumerity™ (diroximel fumarate)
• Vyleesi Vyleesi ™ (bremelanotide)
• Vyndaqel Vyndamax Vyndaqel® (tafamidis meglumine); Vyndamax™ (tafamidis)
• Vyxeos Vyxeos™ (daunorubicin and cytarabine) liposome for injection

• Wakix Wakix® (pitolisant)
• Xalkori Xalkori® (crizotinib)
• Xcopri Xcopri® (cenobamate)
• Xeljanz Xeljanz®, Xeljanz® XR (tofacitinib)
• Xenazine Xenazine®, tetrabenazine
• Xepi Xepi™ (oxenoxacin)
• Xermelo Xermelo™ (telotristat ethyl)
• Xhance Xhance® (fluticasone propionate)
• Xiaflex Xiaflex® (collagenase clostridium histolyticum)
• Xifaxan Xifaxan® (rifaximin)
• Xolair Xolair® (omalizumab)
• Xospata Xospata® (gilteritinib)
• Xpovio Xpovio™ (selinexor)
• Xtandi Xtandi® (enzalutamide)
• Yervoy Yervoy™ (ipilimumab)
• Yescarta Yescarta® (axicabtagene ciloleucel)
• Yondelis Yondelis® (trabectedin)
• Yutiq Yutiq™ (fluocinolone acetonide intravitreal implant)
• Zaltrap Zaltrap® (ziv-aflibercept)
• Zejula Zejula® (niraparib)
• Zelboraf Zelboraf™ (vemurafenib)
• Zepatier Zepatier® (elbasvir and grazoprevir tablets)
• Zeposia Zeposia® (ozanimod)
• Zepzelca Zepzelca™ (lurbinectedin)
• Zinplava Zinplava™ (bezlotoxumab)
• Zokinvy Zokinvy™ (lonafarnib)
• Zolgensma Zolgensma® (onasemnogene abeparvovec-xioi)
• Zolinza Zolinza® (vorinostat)
• Zulresso Zulresso™ (brexanolone) injection
• Zydelig Zydelig® (idelalisib)
• Zykadia Zykadia® (ceritinib)
• Zyvox Zyvox®, linezolid