Henoch-Schonlein purpura

Definition

Henoch-Schonlein purpura is a disease that has the symptoms of purple spots on the skin, joint pain, gastrointestinal symptoms, and glomerulonephritis (a type of kidney disorder).

Alternative Names

Anaphylactoid purpura; Vascular purpura

Causes

Henoch-Schonlein is a type of hypersensitivity vasculitis and inflammatory response within the blood vessel. It is caused by an abnormal response of the immune system. The exact cause for this disorder is unknown.

The syndrome is usually seen in children, but people of any age may be affected. It is more common in boys than in girls. Many people with Henoch-Schonlein purpura had an upper respiratory illness in the previous weeks.

Symptoms

Exams and Tests

Treatment

There is no specific treatment for this disorder. Most cases resolve spontaneously without treatment. If symptoms persist, therapy with corticosteroids such as prednisone is usually tried.

Outlook (Prognosis)

The disease usually resolves spontaneously without treatment.

Possible Complications

When to Contact a Medical Professional


Review Date: 8/14/2003
Reviewed By: Megan E. B. Clowse, M.D., M.P.H., Division of Rheumatology, Johns Hopkins Hospital, Baltimore, MD. Review provided by VeriMed Healthcare Network.
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